GJP: Gap Junction Protein and Its Role in Cell-cell Communication

Target Name: Gap Junction Protein

NCBI ID: P11190

Gap Junction Protein

Other Name(s): None

GJP: Gap Junction Protein and Its Role in Cell-cell Communication

Gap junction protein (GJP) is a protein that plays a crucial role in the regulation of cell-cell communication and is a key player in the development and maintenance of tissues and organs. GJP is a transmembrane protein that forms gap junctions, which are specialized junctions that allow cells to exchange genetic and signaling molecules.

GJP is a family of proteins that includes four isoforms: GJP1, GJP2, GJP3, and GJP4. GJP1 and GJP2 are predominantly expressed in the brain, while GJP3 and GJP4 are expressed in various tissues and organs, including the heart, liver, and kidney.

GJP is involved in a wide range of physiological processes that are critical for the development and maintenance of tissues and organs. One of the key functions of GJP is its role in cell-cell communication. GJP helps to regulate the movement of ions and molecules across the membrane and also plays a role in the transport of various signaling molecules, including neurotransmitters and hormones.

In addition to its role in cell-cell communication, GJP is also involved in the regulation of cell proliferation and cell death. GJP has been shown to play a negative role in the development of cancer and has been shown to promote the growth and survival of cancer cells.

GJP is also involved in the regulation of the immune response and has been shown to play a key role in the development and regulation of immune cell populations. GJP has been shown to regulate the movement of immune cells to the site of an infection and to play a role in the regulation of the production of antibodies by immune cells.

GJP is a potential drug target and has been shown to be involved in a wide range of diseases and conditions. For example, GJP has been shown to be involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. GJP has also been shown to be involved in the development and progression of heart disease, including hypertension and angina.

In addition to its potential clinical applications, GJP is also an important biomarker for the diagnosis and monitoring of various diseases. For example, GJP has been shown to be involved in the development and progression of cancer and has been used as a biomarker for the diagnosis and treatment of various cancers, including breast, ovarian, and prostate cancers.

GJP is a complex protein that plays a crucial role in the regulation of cell-cell communication and is involved in a wide range of physiological processes that are critical for the development and maintenance of tissues and organs. Its potential as a drug target and biomarker make it an attractive target for further research and development.

Protein Name: Gap Junction Protein (nonspecified Subtype)

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•   general information;
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•   expression level;
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